N-[N-[N-(3-Hydroxy-4-methyl-1-oxooctyl)-L-tryptophyl]-L-phenylalanyl]-D-alloisoleucine λ-lactone
Names
[ CAS No. ]:
76265-41-3
[ Name ]:
N-[N-[N-(3-Hydroxy-4-methyl-1-oxooctyl)-L-tryptophyl]-L-phenylalanyl]-D-alloisoleucine λ-lactone
[Synonym ]:
(3R,6S,9S)-6-Benzyl-3-((R)-sec-butyl)-9-(1H-indol-3-ylmethyl)-13-(1-methyl-pentyl)-1-oxa-4,7,10-triaza-cyclotridecane-2,5,8,11-tetraone
Biological Activity
[Description]:
Beauverolide Ja, a cyclotetradepsipeptide, is a potent calmodulin (CaM) inhibitor with a Kd of 0.078 μM and a Ki of 0.39 μM for Ca2+-CaM. Beauverolide Ja is a secondary metabolite of Isaria fumosorosea[1].
[Related Catalog]:
[Target]
Fungal Metabolite
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C35H46N4O5
[ Molecular Weight ]:
602.76400
[ Exact Mass ]:
602.34700
[ PSA ]:
129.39000
[ LogP ]:
5.58180
Related Compounds
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