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Substance P-methyl ester

Names

[ CAS No. ]:
76260-78-1

[ Name ]:
Substance P-methyl ester

[Synonym ]:
L-Arg-L-Pro-L-Lys-L-Pro-Gln-L-Gln-L-Phe-L-Phe-Gly-L-Leu-L-Met-OMe
SP methyl ester
SUBSTANCE P METHYL ESTER
Substance P,[Met-OMet11]
H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME
L-Arg-L-Pro-L-Lys-L-Pro-L-Glu(NH2)-L-Glu(NH2)-L-Phe-L-Phe-Gly-L-Leu-L-Met-OMe
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-OMe,Substance P methyl ester
methylester-substance
substance P-O-methyl ester
ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME
[Met-OMe11]-substance P

Biological Activity

[Description]:

Substance P, [Met-OMet11] is a selective SP-P agonist. Substance P, [Met-OMet11] also is an active peptide. Substance P, [Met-OMet11] can be used for various biochemical studies[1][2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Substance P, [Met-OMet11] (substance P Me ester) 在刺激流涎和回肠收缩方面的效力为 30%[1]。

[References]

[1]. M A Cascieri, et al. Biological activity of substance P methyl ester. Mol Pharmacol  

[2]. C M Lee, et al. Multiple tachykinin binding sites in peripheral tissues and in brain. Eur J Pharmacol. 1986 Nov 4;130(3):209-17.  

Chemical & Physical Properties

[ Density]:
1.41g/cm3

[ Molecular Formula ]:
C64H99N17O14S

[ Molecular Weight ]:
1362.64000

[ Exact Mass ]:
1361.73000

[ PSA ]:
525.14000

[ LogP ]:
4.18150

[ Index of Refraction ]:
1.653

Safety Information

[ WGK Germany ]:
3

Synthetic Route


Related Compounds

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