α-Aminoadipic acid

Names

[ Name ]:
α-Aminoadipic acid

[Synonym ]:
2-Aminohexanedioic acid
2-aminoadipic acid
AAD
DL-2-Aminohexanedioic acid
Hexanedioic acid, 2-amino-, (2R)-
D-2-Aminoadipic Acid
D-2-AMINOADIPIC ACID 98
Hexanedioic acid, 2-amino-
α-Amino-adipic acid
.α.-Aminoadipic acid
UNII:1K7B1OED4N
DL-2-Aminoadipic acid
DL-a-aminoadipic acid
D-aminohexanoic diacid
D-Homoglutamic acid
a-Aminoadipic acid
(2R)-2-Aminohexanedioic acid
H-D-2-Aad-OH
(±)-2-Aminoadipic acid
D-a-Aminoadipic acid
MFCD00063118

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
364.0±32.0 °C at 760 mmHg

[ Melting Point ]:
208-210 °C(lit.)

[ Molecular Formula ]:
C₆H₁₁NO₄

[ Molecular Weight ]:
161.156

[ Flash Point ]:
173.9±25.1 °C

[ Exact Mass ]:
161.068802

[ PSA ]:
100.62000

[ LogP ]:
-0.54

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.515

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Inhibition of the glutamate transporter and glial enzymes in rat striatum by the gliotoxin, alpha aminoadipate.

Br. J. Pharmacol. 113 , 536-540, (1994)

1. The effect of the gliotoxic analogue of glutamate, alpha aminoadipate, on the high affinity transport of D-[3H]-aspartate into a crude striatal P2 preparation, and on the activity of two enzymes of...

The glio-toxic mechanism of alpha-aminoadipic acid on cultured astrocytes.

J. Neurocytol. 27 , 109, (1998)

The mechanism of action of the glutamate analogue alpha-aminoadipic (AAA) acid was investigated in terms of its toxicity to cultured astrocytes. AAA was more toxic to type 1 astrocytes than type 2 ast...

The effects of D-alpha-aminoadipic acid on long-term potentiation in the hippocampus of the rat in vitro.

J. Neurosci. Res. 24 , 139-150, (1996)

Many studies on long-term potentiation (LTP) in hippocampal region CA1 focus on receptor-mediated events that are often presumed to be linked to postsynaptic processes. Whereas it is now well-known th...