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oxycodone

Names

[ CAS No. ]:
76-42-6

[ Name ]:
oxycodone

[Synonym ]:
Thecodine
Tekodin
Oxycodon
(5α)-14-hydroxy-17-methyl-3-(methyloxy)-4,5-epoxymorphinan-6-one
14-hydroxy-dihydrocodeinone
Oxycon
Oxikon
Eubine
oxanest
(1S,5R,13R,17S)-17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0.0.0]octadeca-7(18),8,10-trien-14-one
Eucodalum
Eukodal
oxycodone
Oxicon
(-)-14-Hydroxydihydrocodeinone
Dihydrone
percocet
(1S,5R,13R,17S)-17-Hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0.0.0]octadeca-7(18),8,10-trien-14-on
Tecodin
Thekodin
Percodan
Oxicone
Morphinan-6-one, 4,5α-epoxy-14-hydroxy-3-methoxy-17-methyl-
(1S,5R,13R,17S)-17-hydroxy-10-méthoxy-4-méthyl-12-oxa-4-azapentacyclo[9.6.1.0.0.0]octadéca-7(18),8,10-trién-14-one
Morphinan-6-one, 4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, (5α)-
Morphinan-6-one,4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, (5a)-
Eutagen
(5α)-14-Hydroxy-3-methoxy-17-methyl-4,5-epoxymorphinan-6-one
14-Hydroxydihydrocodeinone
Dihydrohydroxycodeinone
(5a)-4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
endone
EINECS 200-960-2

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
501.6±50.0 °C at 760 mmHg

[ Melting Point ]:
218-220°

[ Molecular Formula ]:
C18H21NO4

[ Molecular Weight ]:
315.364

[ Flash Point ]:
257.1±30.1 °C

[ Exact Mass ]:
315.147064

[ PSA ]:
59.00000

[ LogP ]:
1.67

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.659

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QD2450000
CHEMICAL NAME :
Morphinan-6-one, 4,5-alpha-epoxy-14-hydroxy-3-methoxy-17-methyl-
CAS REGISTRY NUMBER :
76-42-6
BEILSTEIN REFERENCE NO. :
0043446
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C18-H21-N-O4
MOLECULAR WEIGHT :
315.40
WISWESSER LINE NOTATION :
T B6566 B6/CO 4ABBC R BX FV HO PN GHT&&TTJ CQ JO1 P1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,261,1961
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
426 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
28ZNAE "Public Health Reports, Supplement." (Washington, DC) Volume(issue)/page/year: 138,27,1938

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Precautionary Statements ]:
P301 + P312 + P330

[ Hazard Codes ]:
F,T

[ Risk Phrases ]:
11-23/24/25-39/23/24/25

[ Safety Phrases ]:
7-16-36/37-45

[ RIDADR ]:
UN 1544

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)

Synthetic Route

Precursor & DownStream

Articles

Inhibition of TRPM8 channels reduces pain in the cold pressor test in humans.

J. Pharmacol. Exp. Ther. 351(2) , 259-69, (2014)

The transient receptor potential (subfamily M, member 8; TRPM8) is a nonselective cation channel localized in primary sensory neurons, and is a candidate for cold thermosensing, mediation of cold pain...

Spontaneous resolution of quadrilateral space syndrome: a case report.

Am. J. Phys. Med. Rehabil. 94(1) , e1-5, (2015)

A case of quadrilateral space syndrome is presented, where a large near-circumferential glenoid labrum tear led to a paralabral cyst that dissected into the quadrilateral space and caused a compressiv...

Rational prescribing.

Minn. Med. 96(3) , 4, (2013)


More Articles


Related Compounds

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