phenyl-(3-phenyloxiran-2-yl)methanone
Names
[ CAS No. ]:
7570-86-7
[ Name ]:
phenyl-(3-phenyloxiran-2-yl)methanone
[Synonym ]:
TRANS-2-BENZOYL-3-PHENYLOXIRANE
trans-2-Benzoyl-3-phenyloxirane,trans-Benzalacetophenone oxide
2,4,4-TRIMETHYL-1-PENTENE (NO BULK SALES ALLOWED)
TRANS-BENZALACETOPHENONE OXIDE
trans-chalconeoxide
trans-2,3-epoxy-1,3-diphenyl-1-propanone
TRANS-1,3-DIPHENYL-2,3-EPOXYPROPAN-1-ONE
trans-phenyl(3-phenyloxiranyl)methanone
3-epoxy-3-phenyl-trans-propiophenon
Chemical & Physical Properties
[ Density]:
1.209g/cm3
[ Boiling Point ]:
374.1ºC at 760 mmHg
[ Melting Point ]:
86-89ºC(lit.)
[ Molecular Formula ]:
C15H12O2
[ Molecular Weight ]:
224.25500
[ Flash Point ]:
174ºC
[ Exact Mass ]:
224.08400
[ PSA ]:
29.60000
[ LogP ]:
3.00940
[ Index of Refraction ]:
1.617
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UH1589300
- CHEMICAL NAME :
- Propiophenone, 2,3-epoxy-3-phenyl-, trans-
- CAS REGISTRY NUMBER :
- 7570-86-7
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C15-H12-O2
- MOLECULAR WEIGHT :
- 224.27
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 mg/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 169,71,1986
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
22-24/25
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
UH1589300
Articles
Angew. Chem. Int. Ed. Engl. 44(9) , 1383-5, (2005)
Anti-inflammatory effects of trans-1,3-diphenyl-2,3-epoxypropane-1-one mediated by suppression of inflammatory mediators in LPS-stimulated RAW 264.7 macrophages.
Food Chem. Toxicol. 53 , 371-5, (2013)
To assess the potential therapeutic properties of trans-1,3-diphenyl-2,3-epoxypropane-1-one (DPEP), its anti-inflammatory effects were investigated in lipopolysaccharide (LPS)-stimulated mouse macroph...
Structure-mutagenicity relationships of chalcones and their oxides in the Salmonella assay.Mutat. Res. 169(3) , 71-9, (1986)
31 p-monosubstituted chalcones (E-1, 3-diphenylpropene-1-one) and the corresponding oxides (E-1-benzoyl-2-phenyloxirane) were tested for mutagenic activity on two strains of Salmonella typhimurium (TA...