Tropodithietic acid

Names

[ Name ]:
Tropodithietic acid

[Synonym ]:
tropodithietic acid
3-Oxo-8,9-dithiabicyclo[5.2.0]nona-1,4,6-triene-2-carboxylic acid
8,9-Dithiabicyclo[5.2.0]nona-1,4,6-triene-2-carboxylic acid, 3-oxo-

Biological Activity

[Description]:

Tropodithietic acid is a sulfur-containing antibiotic produced by the marine bacterium Phaeobacter inhibens. Tropodithietic acid exhibits a strong antibiotic activity against a broad spectrum of bacteria including alpha- and gammaproteobacteria, flavobacteria and actinobacteria[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Rabe P, et al. Synthesis and bioactivity of analogues of the marine antibiotic tropodithietic acid. Beilstein J Org Chem. 2014 Aug 6;10:1796-801.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
435.6±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₈H₄O₃S₂

[ Molecular Weight ]:
212.246

[ Flash Point ]:
217.2±31.5 °C

[ Exact Mass ]:
211.960190

[ LogP ]:
1.40

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.784

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

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