Isometheptene Mucate

Names

[ Name ]:
Isometheptene Mucate

[Synonym ]:
Galaktarsure,Verbindung mit N,1,5-Trimethylhex-4-en-1-ylamin (1:2)
n,1,5-trimethyl-4-hexenylamingalactarate(2:1)
N,1,5-Trimethyl-4-hexenylamine galactarate (2:1)
octinmucate
n,1,5-trimethyl-4-hexenylaminemucate
n,1,5-trimethyl-4-hexenylamincompd.withgalactaricacid(2:1)
galactaricacid,compd.withn,1,5-trimethyl-4-hexenylamine(1:2)
n,1,5-trimethyl-4-hexenylaminmucate(2:1)

Biological Activity

[Description]:

Isometheptene mucate, a sympathomimetic agent, is a indirect-acting adrenergic receptor agonist. Isometheptene mucate can be used for migraine research[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

Research Areas >> Neurological Disease

[References]

[1]. Alejandro Labastida-Ramírez, et al. Effects of two isometheptene enantiomers in isolated human blood vessels and rat middle meningeal artery - potential antimigraine efficacy. J Headache Pain. 2019 May 3;20(1):47. https://pubmed.ncbi.nlm.nih.gov/31053059/

Chemical & Physical Properties

[ Boiling Point ]:
706.9ºC at 760 mmHg

[ Molecular Formula ]:
C₂₁H₃₉NO₁₆

[ Molecular Weight ]:
561.53100

[ Flash Point ]:
381.3ºC

[ Exact Mass ]:
561.22700

[ PSA ]:
323.07000

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LW5250000

CAS REGISTRY NUMBER :: 7492-31-1

LAST UPDATED :: 199012

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C18-H38-N2.C6-H10-O8

MOLECULAR WEIGHT :: 492.74

WISWESSER LINE NOTATION :: 1Y&U3YM1 & 2 &621 QVYQYQ 2 -ABBA &622

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 148 mg/kg

TOXIC EFFECTS :: Gastrointestinal - nausea or vomiting

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 92,214,1948

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Precautionary Statements ]:
P301 + P312 + P330

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
40

[ Safety Phrases ]:
22-36

[ RIDADR ]:
NONH for all modes of transport