Nerindocianine

Names

[ Name ]:
Nerindocianine

[Synonym ]:
3H-Indolium, 2-[(E)-2-[3-[(2E)-2-[1,3-dihydro-3,3-dimethyl-5-sulfo-1-(4-sulfobutyl)-2H-indol-2-ylidene]ethylidene]-2-(4-sulfophenoxy)-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-5-sulfo-1-(4-sulfobutyl)-, inner salt
Irdye 800Bk
4-(2-{(E)-2-[3-{(2E)-2-[3,3-Dimethyl-5-sulfo-1-(4-sulfobutyl)-1,3-dihydro-2H-indol-2-ylidene]ethylidene}-2-(4-sulfophenoxy)-1-cyclohexen-1-yl]vinyl}-3,3-dimethyl-5-sulfo-3H-indolium-1-yl)-1-butanesulfonate

Biological Activity

[Description]:

Nerindocianine is a fluorescent diagnostic contrast agent. Nerindocianine is highly hydrophilic and is primarily metabolized by the kidneys, allowing for a non-invasive intraoperative ureteral imaging[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vivo]

Nerindocianine (0.15 mg/kg; i.v.) shows a satisfactory visualization[1]. Animal Model: Female pigs[1] Dosage: 0.15 mg/kg Administration: I.v. Result: Showed a satisfactory visualization.

[References]

[1]. Barberio M, et al. Intraoperative ureter identification with a novel fluorescent catheter. Sci Rep. 2021;11(1):4501. Published 2021 Feb 24.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₄H₅₂N₂O₁₆S₅

[ Molecular Weight ]:
1025.21

[ Exact Mass ]:
1024.192017

Related Compounds

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