Hydrocortisone aceponate

Names

[ Name ]:
Hydrocortisone aceponate

[Synonym ]:
hydrocortisone aceponate
[(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
propionic acid [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetoxyacetyl)-11-hydroxy-3-keto-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] ester
[(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyethanoyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
Hydrocortison-17-propionat-21-acetat

Biological Activity

[Description]:

Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid. Hydrocortisone aceponate can be used for various dermatoses research[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor

[References]

[1]. Amiya Kumar Mukhopadhyay, et al. A study to evaluate the efficacy and safety of hydrocortisone aceponate 0.127% lipophilic cream in steroid responsive dermatoses in Indian patients. Indian J Dermatol Venereol Leprol. Sep-Oct 2010;76(5):591.

Chemical & Physical Properties

[ Density]:
1.23g/cm3

[ Boiling Point ]:
589.3ºC at 760 mmHg

[ Melting Point ]:
144-146ºC

[ Molecular Formula ]:
C₂₆H₃₆O₇

[ Molecular Weight ]:
460.56000

[ Flash Point ]:
192.4ºC

[ Exact Mass ]:
460.24600

[ PSA ]:
106.97000

[ LogP ]:
3.31330

[ Index of Refraction ]:
1.552

Related Compounds

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