11-Oxo etiocholanolone

Names

[ CAS No. ]:
739-27-5

[ Name ]:
11-Oxo etiocholanolone

[Synonym ]:
Oxoetiocholanolone
11-ketoetioholanolone
11-Ketoaetiocholanolone
5-Androstan-3a-ol-11,17-dione-d5
Etiocholanol-11-one
11-oxo-etiocholanolone
11-KETOETIOCHOLANOLONE
11-Oxoaetiocholanolone
3-Hydroxyandrostane-11,17-dione

Biological Activity

[Description]:

11-Oxo etiocholanolone (11-Ketoetiocholanolone) is a metabolite of Etiocholanolone. Etiocholanolone is the excreted metabolite of testosterone and has anticonvulsant activity[1][2].

[Related Catalog]:

Research Areas >> Endocrinology

Research Areas >> Neurological Disease

[References]

[1]. Wesley J Arbuckle, et al. In Vitro Biosynthesis of Novel 5beta-reduced Steroids by the Testis of the Round Goby, Neogobius Melanostomus. Gen Comp Endocrinol. 2005 Jan 1;140(1):1-13.

[2]. Ping Li,et al. Natural and Enantiomeric Etiocholanolone Interact With Distinct Sites on the Rat alpha1beta2gamma2L GABAA Receptor. Mol Pharmacol. 2007 Jun;71(6):1582-90.

Chemical & Physical Properties

[ Density]:
1.152g/cm3

[ Boiling Point ]:
453.4ºC at 760 mmHg

[ Melting Point ]:
186-189°C (lit.)

[ Molecular Formula ]:
C₁₉H₂₈O₃

[ Molecular Weight ]:
304.42400

[ Flash Point ]:
242.1ºC

[ Exact Mass ]:
304.20400

[ PSA ]:
54.37000

[ LogP ]:
3.13810

[ Index of Refraction ]:
1.545

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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