H-His-OMe.2HCl

Names

[ Name ]:
H-His-OMe.2HCl

[Synonym ]:
L-Histidine, methyl ester, dihydrochloride
H-L-His-OMe dihydrochloride
L-Histidine Methyl Ester 2HCl
H-His-OMe dihydrochloride
EINECS 230-973-9
HISTIDINE-OME 2 HCL
H-His-OMe.2HCI
H-L-HIS-OME 2HCL
L-Histidine methyl e
L-HISTIDINE METHYL ESTER DIHCL
H-His-OMe.2HCl
H-His-OMe,2HCl
MethylL-histidinatedihydrochloride
Histidine methyl ester 2HCI
MFCD00012701
L-histidine methyl ester dihydrochloride salt
Methyl L-histidinate dihydrochloride
(S)-Methyl 2-amino-3-(1H-imidazol-4-yl)propanoate dihydrochloride
L-Histidine, methyl ester, hydrochloride (1:2)
H-His-OMe·2HCl

Biological Activity

[Description]:

Methyl L-histidinate dihydrochloride is a histidine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Boiling Point ]:
368.2ºC at 760 mmHg

[ Melting Point ]:
207 °C (dec.)(lit.)

[ Molecular Formula ]:
C₇H₁₃Cl₂N₃O₂

[ Molecular Weight ]:
242.103

[ Flash Point ]:
176.5ºC

[ Exact Mass ]:
241.038483

[ PSA ]:
81.00000

[ LogP ]:
1.75680

[ Index of Refraction ]:
10 ° (C=2, H2O)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933290090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Preparation and use of poly(hydroxyethyl methacrylate) cryogels containing L-histidine for β-casein adsorption.

J. Food Sci. 78(2) , E238-43, (2013)

The objective of this study was to determine β-casein adsorption by using supermacroporous poly(2-hydroxyethyl methacrylate-N-methacryloyl-(l)-histidine methyl ester) [p(HEMA-MAH)] cryogel. β-Casein a...

A proximal pair of positive charges provides the dominant ligand-binding contribution to complement-like domains from the LRP (low-density lipoprotein receptor-related protein).

Biochem. J. 443(1) , 65-73, (2012)

The LRP (low-density lipoprotein receptor-related protein) can bind a wide range of structurally diverse ligands to regions composed of clusters of ~40 residue Ca2+-dependent, disulfide-rich, CRs (com...

The biological activity of hydrogen peroxide. IV. Enhancement of its clastogenic actions by coadministration of L-histidine.

Mutat. Res. 198(1) , 233-40, (1988)

An enhancing effect of L-histidine (L-His) was detected on the induction by hydrogen peroxide (H2O2) of chromosomal aberrations of both the chromosome type and the chromatid type, in human embryonic f...