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27-p-Coumaroyloxyursolic acid

Names

[ CAS No. ]:
73584-67-5

[ Name ]:
27-p-Coumaroyloxyursolic acid

[Synonym ]:
Urs-12-en-28-oic acid, 3-hydroxy-27-[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-, (3β,5ξ)-
(3β,5ξ)-3-Hydroxy-27-{[(2E)-3-(4-hydroxyphenyl)-2-propenoyl]oxy}urs-12-en-28-oic acid

Biological Activity

[Description]:

27-p-Coumaroyloxyursolic acid (compound 6) is a kind of ulmoidol. 27-p-Coumaroyloxyursolic acid can be isolated from Ilex kudincha. 27-p-Coumaroyloxyursolic acid is an inhibitor of Acyl CoA Cholesteryl Acyl Transferase (ACAT) with an IC50 value of 0.73 μM[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. K Nishimura, et al. Activity-guided isolation of triterpenoid acyl CoA cholesteryl acyl transferase (ACAT) inhibitors from Ilex kudincha. J Nat Prod. 1999, 62, 7.  

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
726.7±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C39H54O6

[ Molecular Weight ]:
618.843

[ Flash Point ]:
218.6±26.4 °C

[ Exact Mass ]:
618.392029

[ PSA ]:
104.06000

[ LogP ]:
9.47

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.597

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds