Orniplabin

Names

[ Name ]:
Orniplabin

Biological Activity

[Description]:

Orniplabin (SMTP-7) is a low-molecular-weight compound that enhances plasminogen–fibrin binding, urokinase-catalyzed activation of plasminogen, and urokinase and plasminogen-mediated fibrin degradation. Orniplabin shows potential thrombolytic and anti-inflammatory effects. Orniplabin inhibits ROS[1][2].

[Related Catalog]:

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

[References]

[1]. Shibata K, et al. A novel finding of a low-molecular-weight compound, SMTP-7, having thrombolytic and anti-inflammatory effects in cerebral infarction of mice. Naunyn Schmiedebergs Arch Pharmacol. 2010 Sep;382(3):245-53.

[2]. Shibata K, et al. Neuroprotective mechanisms of SMTP-7 in cerebral infarction model in mice. Naunyn Schmiedebergs Arch Pharmacol. 2011 Jul;384(1):103-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₁H₆₈N₂O₁₀

[ Molecular Weight ]:
869.09