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Pentafluorobenzenesulfonyl fluorescein

Names

[ CAS No. ]:
728912-45-6

[ Name ]:
Pentafluorobenzenesulfonyl fluorescein

[Synonym ]:
6'-Hydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-3'-yl pentafluorobenzenesulfonate
Hydrogen Peroxide Probe,Fluorogenic
Pentafluorobenzenesulfonyl fluorescein
Benzenesulfonic acid, 2,3,4,5,6-pentafluoro-, 6'-hydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl ester

Biological Activity

[Description]:

Pentafluorobenzenesulfonyl fluorescein is a H2O2-selective sensor that can be used to detect H2O2 levels in cells. Pentafluorobenzenesulfonyl fluorescein is normally non-fluorescent but fluoresces upon perhydrolysis of the sulfonyl linkage by H2O2[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Ashley L Waldron, et al. Oxidative stress-dependent MMP-13 activity underlies glucose neurotoxicity. J Diabetes Complications. 2018 Mar;32(3):249-257.

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
707.3±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C26H11F5O7S

[ Molecular Weight ]:
562.42

[ Flash Point ]:
381.6±32.9 °C

[ Exact Mass ]:
562.014587

[ PSA ]:
107.51000

[ LogP ]:
5.08

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.702

[ Storage condition ]:
-20°C

Related Compounds