(r)-(+)-1-amino-2-(methoxymethyl)pyrrolidine

Names

[ Name ]:
(r)-(+)-1-amino-2-(methoxymethyl)pyrrolidine

[Synonym ]:
(2R)-2-(Methoxymethyl)-1-pyrrolidinamine
(R)-(+)-1-Amino-2-(methoxymethyl)pyrrolidine
MFCD00010622
(2R)-2-(Methoxymethyl)pyrrolidin-1-amine
1-Pyrrolidinamine, 2-(methoxymethyl)-, (2R)-

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
183.7±13.0 °C at 760 mmHg

[ Molecular Formula ]:
C₆H₁₄N₂O

[ Molecular Weight ]:
130.188

[ Flash Point ]:
64.9±19.8 °C

[ Exact Mass ]:
130.110611

[ PSA ]:
38.49000

[ LogP ]:
-1.25

[ Vapour Pressure ]:
0.8±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.470

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

SCF ubiquitin ligase-targeted therapies.

Nat. Rev. Drug Discov. 13(12) , 889-903, (2014)

The clinical successes of proteasome inhibitors for the treatment of cancer have highlighted the therapeutic potential of targeting this protein degradation system. However, proteasome inhibitors prev...

Endogenous VMH amylin signaling is required for full leptin signaling and protection from diet-induced obesity.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 310 , R355-65, (2016)

Amylin enhances arcuate (ARC) and ventromedial (VMN) hypothalamic nuclei leptin signaling and synergistically reduces food intake and body weight in selectively bred diet-induced obese (DIO) rats. Sin...