4-Aminophenyl disulfide
Names
[ CAS No. ]:
722-27-0
[ Name ]:
4-Aminophenyl disulfide
[Synonym ]:
Dithioaniline
4,4'-Diaminodiphenyl disulphide
4-Aminophenyl disulfide
p-p'-Dithiodianiline
4,4'-Dithio-Aniline
4-aminophenyl
{4-[(4-Aminophenyl)dithio]phenyl}amine
4,4'-Disulfanediyldianiline
MFCD00007882
Benzenamine, 4,4'-dithiobis-
EINECS 211-961-2
4,4'-diamino diphenyl disulfide
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
447.0±30.0 °C at 760 mmHg
[ Melting Point ]:
77-78 °C(lit.)
[ Molecular Formula ]:
C12H12N2S2
[ Molecular Weight ]:
248.367
[ Flash Point ]:
224.2±24.6 °C
[ Exact Mass ]:
248.044189
[ PSA ]:
102.64000
[ LogP ]:
1.65
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.741
[ Stability ]:
Stable. Incompatible with acids, acid chlorides, acid anhydrides, chloroformates, strong oxidizing agents. Sensitive to air.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BX9580000
- CHEMICAL NAME :
- Aniline, p,p'-dithiodi-
- CAS REGISTRY NUMBER :
- 722-27-0
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C12-H12-N2-S2
- MOLECULAR WEIGHT :
- 248.38
- WISWESSER LINE NOTATION :
- ZR DSSR DZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 434 mg/kg/7D-I
- TOXIC EFFECTS :
- Endocrine - changes in adrenal weight Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - changes in iron
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 100 ug/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 67,123,1979
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
BX9580000
[ Hazard Class ]:
9.0
[ HS Code ]:
2930909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2930909090
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Blood 73(1) , 312-7, (1989)
It has been shown that certain dogs have erythrocytes characterized by an inherited high concentration of reduced glutathione (GSH), five to seven times the normal level (high-GSH RBCs). We examined w...
Kinetics of polymerization of hemoglobin S modified by thiol reagents and by oxidation.Biochim. Biophys. Acta 830(1) , 71-9, (1985)
The effects of four thiol reagents on the kinetics of polymerization of hemoglobin S have been studied in high phosphate buffer (1.8 M), in the presence (3 mM) or absence of sodium dithionite, dependi...