Acetophenone-13C

Names

[ CAS No. ]:
71777-36-1

[ Name ]:
Acetophenone-13C

[Synonym ]:
1-phenyl-[2-13C]ethanone
[8-13C]acetophenone
Acetophenone-|A-13C
Acetophenone-(methyl-13C)
MFCD00064444

Biological Activity

[Description]:

Acetophenone-13C is the 13C labeled Acetophenone[1]. Acetophenone is an organic compound with simple structure[2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Żymańczyk-Duda E, et al. Reductive capabilities of different cyanobacterial strains towards acetophenone as a model substrate - Prospect of applications for chiral building blocks synthesis. Bioorg Chem. 2019 Feb 25. pii: S0045-2068(18)31467-6.  

Chemical & Physical Properties

[ Density]:
1.038 g/mL at 25ºC

[ Boiling Point ]:
202ºC(lit.)

[ Melting Point ]:
19-20ºC(lit.)

[ Molecular Formula ]:
C8H8O

[ Molecular Weight ]:
121.14100

[ Flash Point ]:
180 °F

[ Exact Mass ]:
121.06100

[ PSA ]:
17.07000

[ LogP ]:
1.88920

[ Index of Refraction ]:
n20/D 1.5335(lit.)

MSDS

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Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
26

[ RIDADR ]:
UN 3334

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Related Compounds