FOY 251 free base

Names

[ Name ]:
FOY 251 free base

[Synonym ]:
p-(p-Guanidinbenzoyloxy)-phenylessigsaeure
4-Fluor-4'-hydroxydiphenylether
4-(4-guanidinobenzoyloxy) phenylacetate
p-(p-guanidinobenzoyloxy)phenylacetic acid
p-(p-fluorophenoxy)phenol
4-(4-Fluoro-phenoxy)-phenol
Phenol,4-(4-fluorophenoxy)

Biological Activity

[Description]:

FOY 251 free base is an anti-proteolytic active metabolite camostate (HY-13512), acts as a proteinase inhibitor[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[In Vitro]

FOY 251 free base represents a dose-dependent inhibition of equivalent current in M-1 cells[2]. FOY-251 free base inhibits the proteolytic activity of prostasin[2].

[References]

[1]. K Beckh, et al. Elimination of the Low-Molecular Weight Proteinase Inhibitor Camostate (FOY 305) and Its Degradation Products by the Rat Liver. Res Exp Med (Berl). 1987;187(6):401-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₅N₃O₄

[ Molecular Weight ]:
313.30800

[ Exact Mass ]:
313.10600

[ PSA ]:
125.50000

[ LogP ]:
2.71130

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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