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AQ4

Names

[ CAS No. ]:
70476-63-0

[ Name ]:
AQ4

Biological Activity

[Description]:

AQ4 is a topoisomerase II inhibitor and DNA intercalator as a chemically stable cytotoxic agent in many human tumor lines[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase

[Target]

Topoisomerase II


[References]

[1]. Luan X, et al. A Tumor Vascular-Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia. Adv Sci (Weinh). 2018 May 28;5(8):1800034.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H28N4O4

[ Molecular Weight ]:
412.48200

[ Exact Mass ]:
412.21100

[ PSA ]:
105.14000

[ LogP ]:
1.96620

MSDS

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H410

[ Precautionary Statements ]:
P273-P501

[ RIDADR ]:
UN 3077 9 / PGIII

Precursor & DownStream

Precursor

DownStream


Related Compounds

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