10,11-dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine

Names

[ Name ]:
10,11-dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine

[Synonym ]:
DIZOCILPINE
10,11-dihydro-5-methyl-5H-dibenzo<a,d>cyclohepten-5,10-imine
Dizocilpinum
Dizocilpina

Biological Activity

[Description]:

(Rac)-Dizocilpine ((Rac)-MK-801) is the racemate of Dizocilpine (HY-15084B). Dizocilpine (MK-801), a potent anticonvulsant, is a selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Wong EH, et al. The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc Natl Acad Sci U S A. 1986 Sep;83(18):7104-8.

Chemical & Physical Properties

[ Density]:
1.144g/cm3

[ Boiling Point ]:
320.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₆H₁₅N

[ Molecular Weight ]:
221.30

[ Flash Point ]:
152.6ºC

[ Exact Mass ]:
221.12000

[ PSA ]:
12.03000

[ LogP ]:
3.47930

[ Index of Refraction ]:
1.632

Related Compounds

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