3-Amino-1-hydroxyadamantane

Names

[ CAS No. ]:
702-82-9

[ Name ]:
3-Amino-1-hydroxyadamantane

[Synonym ]:
3-aminotricyclo[3.3.1.13,7]decan-1-ol
MFCD01821204
3-Amino-1-hydroxyadamantane
Tricyclo[3.3.1.1]decan-1-ol, 3-amino-, (5R,7S)-
(1s,3r,5R,7S)-3-Amino-1-adamantanol
3-Amino-1-adamantanol
3-aminoadamantan-1-ol
Tricyclo[3.3.1.1]decan-1-ol, 3-amino-
(1S,3R,5R,7S)-3-aminoadamantan-1-ol
tricyclo[3.3.1.13,7]decan-1-ol, 3-amino-
3-Hydroxy 1-amino adamantine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
266.8±23.0 °C at 760 mmHg

[ Melting Point ]:
265 °C (dec.)(lit.)

[ Molecular Formula ]:
C₁₀H₁₇NO

[ Molecular Weight ]:
167.248

[ Flash Point ]:
115.2±22.6 °C

[ Exact Mass ]:
167.131012

[ PSA ]:
46.25000

[ LogP ]:
0.46

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.624

[ Storage condition ]:
2~8℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Adamantyl analogues of paracetamol as potent analgesic drugs via inhibition of TRPA1.

PLoS ONE 9(12) , e113841, (2014)

Paracetamol also known as acetaminophen, is a widely used analgesic and antipyretic agent. We report the synthesis and biological evaluation of adamantyl analogues of paracetamol with important analge...

Liquid chromatographic methods for the determination of vildagliptin in the presence of its synthetic intermediate and the simultaneous determination of pioglitazone hydrochloride and metformin hydrochloride.

Int. J. Biomed. Sci. 7(3) , 201-8, (2011)

Ozone fumigation was explored as a means for degrading organic fungicide residues on fresh produce. Fungicides sorbed onto model abiotic glass surfaces or onto grape berries were fumigated separately ...

Further calculations on solubility of 3-amino-1-adamantanol in ethanol+ water binary solvent mixtures at various temperatures. Jouyban A, et al.

J. Mol. Liq. 219 , 211-215, (2016)