GLX481304

Names

[ Name ]:
GLX481304

Biological Activity

[Description]:

GLX481304 is a specific inhibitor of Nox-2 and -4, with IC50s of 1.25 μM. GLX481304 suppresses ROS production in isolated mouse cardiomyocytes and improves cardiomyocyte contractility. GLX481304 can be used for research of ischemic injury to the heart[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

[Target]

Nox-2/4[1]

[References]

[1]. Szekeres FLM, et al. A small molecule inhibitor of Nox2 and Nox4 improves contractile function after ischemia-reperfusion in the mouse heart. Sci Rep. 2021 Jun 7;11(1):11970.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₉N₇O

[ Molecular Weight ]:
419.52

Related Compounds

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