701224-63-7

701224-63-7 structure

Name: GLX481304
Chemical Name: GLX481304
CAS Number: 701224-63-7
Molecular Formula: C₂₃H₂₉N₇O
Molecular Weight: 419.52
Catalog: Research Areas Cardiovascular Disease
Create Date: 2023-11-11 18:41:28
Modify Date: 2024-01-12 14:08:02
GLX481304 is a specific inhibitor of Nox-2 and -4, with IC50s of 1.25 μM. GLX481304 suppresses ROS production in isolated mouse cardiomyocytes and improves cardiomyocyte contractility. GLX481304 can be used for research of ischemic injury to the heart[1].

Name	GLX481304

Description	GLX481304 is a specific inhibitor of Nox-2 and -4, with IC50s of 1.25 μM. GLX481304 suppresses ROS production in isolated mouse cardiomyocytes and improves cardiomyocyte contractility. GLX481304 can be used for research of ischemic injury to the heart[1].
Related Catalog	Research Areas >> Cardiovascular Disease
Target	Nox-2/4[1]
References	[1]. Szekeres FLM, et al. A small molecule inhibitor of Nox2 and Nox4 improves contractile function after ischemia-reperfusion in the mouse heart. Sci Rep. 2021 Jun 7;11(1):11970.

Molecular Formula	C₂₃H₂₉N₇O
Molecular Weight	419.52