H-Gly-Asp-Asp-Asp-Asp-Lys-βNA ammonium salt

Names

[ CAS No. ]:
70023-02-8

[ Name ]:
H-Gly-Asp-Asp-Asp-Asp-Lys-βNA ammonium salt

[Synonym ]:
MFCD00083712
H-Gly-Asp-Asp-Asp-Asp-Lys-βNA

Biological Activity

[Description]:

Gly-Asp-Asp-Asp-Asp-Lys-β-naphthylamide (GD4K-na) is a substrate for human enteropeptidase (Km: 0.16 mM)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

纯化的重组人肠肽酶轻链 (L-HEP) 以 Km: 0:16 mM 和 kcat: 115 秒的速率裂解 Gly-Asp-Asp-Asp-Asp-Lys-β-naphthylamide[1]。

[References]

[1]. Gasparian ME, et al. Expression, purification, and characterization of human enteropeptidase catalytic subunit in Escherichia coli. Protein Expr Purif. 2003 Sep;31(1):133-9.

Chemical & Physical Properties

[ Density]:
1.468g/cm3

[ Boiling Point ]:
1378.8ºC at 760 mmHg

[ Molecular Formula ]:
C₃₄H₄₄N₈O₁₄

[ Molecular Weight ]:
788.76

[ Flash Point ]:
787.7ºC

[ Exact Mass ]:
788.29800

[ PSA ]:
375.84000

[ LogP ]:
0.61690

[ Index of Refraction ]:
1.631

[ Storage condition ]:
−20°C

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H351

[ Precautionary Statements ]:
P281

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
40

[ Safety Phrases ]:
22-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

DownStream

Articles

The application of a new synthetic substrate to the determination of enteropeptidase in rat small intestine and human intestinal biopsies.

Clin. Chim. Acta 101 , 69, (1980)

The application of a new synthetic substrate to the direct determination of enteropeptidase is described. The substrate Gly-(L-Asp)4-L-Lys-2-naphthylamide contains the amino acid sequence of the activ...

Related Compounds

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