5-Iodouracil
Names
[ CAS No. ]:
696-07-1
[ Name ]:
5-Iodouracil
[Synonym ]:
5-iodopyriMidine-2.4-diol
EINECS 211-788-2
5IU
2,4(1H,3H)-Pyrimidinedione, 5-iodo-
5-iodopyrimidine-2,4-diol
5-Iodo-2,4(1H,3H)-pyrimidinedione
5-IODOURACIL extrapure
5-iodine uracil
5-iodopyrimidine-2,4(1H,3H)-dione
5-iodo-2,4-dioxopyrimidine
4-iodouracil
5-Iodpyrimidin-2,4(1H,3H)-dion
MFCD00006020
5-Iodouracil
2(1H)-pyrimidinone, 4-hydroxy-5-iodo-
5-iodo-uraci
5-iodo uracil
Chemical & Physical Properties
[ Density]:
2.4±0.1 g/cm3
[ Boiling Point ]:
401ºC
[ Melting Point ]:
274-276 °C (dec.)(lit.)
[ Molecular Formula ]:
C4H3IN2O2
[ Molecular Weight ]:
237.983
[ Exact Mass ]:
237.923904
[ PSA ]:
66.24000
[ LogP ]:
0.14
[ Index of Refraction ]:
1.706
[ Storage condition ]:
0-6°C
[ Water Solubility ]:
SOLUBLE IN COLD WATER
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YR0525000
- CHEMICAL NAME :
- Uracil, 5-iodo-
- CAS REGISTRY NUMBER :
- 696-07-1
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C4-H3-I-N2-O2
- MOLECULAR WEIGHT :
- 237.99
- WISWESSER LINE NOTATION :
- T6MVMVJ FI
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 13,1249,1964
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R46;R20/21/22;R36/37/38
[ Safety Phrases ]:
S53-S22-S26-S36/37/39-S45
[ RIDADR ]:
2811
[ WGK Germany ]:
3
[ RTECS ]:
YR0525000
[ HS Code ]:
2933599090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
PLoS ONE 4(3) , e4949, (2009)
Glycerol nucleic acid (GNA) has an acyclic phosphoglycerol backbone repeat-unit, but forms stable duplexes based on Watson-Crick base-pairing. Because of its structural simplicity, GNA is of particula...
Highly hydrophilic and nonionic poly(2-vinyloxazoline)-grafted silica: a novel organic phase for high-selectivity hydrophilic interaction chromatography.Anal. Bioanal. Chem 406(19) , 4585-93, (2014)
A new hydrophilic and nonionic poly(2-vinyloxazoline)-grafted silica (Sil-VOX(n)) phase was synthesized and applied for the separation of nucleosides and nucleobases in hydrophilic interaction chromat...
Preparation and properties of oligodeoxynucleotides containing 5-iodouracil and 5-bromo- and 5-iodocytosine.Bioconjug. Chem. 8(5) , 757-61, (1997)
The behavior of oligonucleotides containing 5-iodouracil, 5-bromocytidine, and 5-iodocytidine in concentrated ammonia is described. 5-Aminouracil and 5-aminocytidine are obtained as side products when...