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Fluroxypyr

Names

[ CAS No. ]:
69377-81-7

[ Name ]:
Fluroxypyr

[Synonym ]:
[(4-Amino-3,5-dichloro-6-fluoropyridin-2-yl)oxy]acetic acid
2-[(4-amino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy]acetic acid
ef-689
4-amino-3,5-dichloro-6-fluoro-pyridin-2-yloxyacetic acid
4-Amino-3,5-dichloro-6-fluoro-2-pyridyloxyacetic acid
[(4-Amino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy]acetic acid
Acetic acid, [(4-amino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy]-
4-amino-3,5-dichloro-6-fluoro-2-pyridyloxyaceticacid
MFCD01311822
ff4014
ADVANCE
Fluroxypyr
Acetic acid, 2-[(4-amino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy]-
4,5-amino-3,5-dichloro-6-fluoro-2-pyridinyloxyacetic acid

Biological Activity

[Description]:

Fluroxypyr is an auxin herbicide to control annual or perennial weeds. Fluroxypyr icauses auxin overdose or excessive endogenous auxin concentrations, thereby resulting in an imbalance of auxin homeostasis and interaction with other hormones in tissues[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Meijun Guo, et al. Comprehensive evaluation of fluroxypyr herbicide on physiological parameters of spring hybrid millet. PeerJ. 2019 Sep 26:7:e7794.  

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
399.4±37.0 °C at 760 mmHg

[ Melting Point ]:
57.5°C

[ Molecular Formula ]:
C7H5Cl2FN2O3

[ Molecular Weight ]:
255.031

[ Flash Point ]:
195.3±26.5 °C

[ Exact Mass ]:
253.966125

[ PSA ]:
85.44000

[ LogP ]:
3.16

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.608

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AF2500000
CHEMICAL NAME :
Acetic acid, ((4-amino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy)-
CAS REGISTRY NUMBER :
69377-81-7
LAST UPDATED :
199412
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C7-H5-Cl2-F-N2-O3
MOLECULAR WEIGHT :
255.04

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2405 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A791,1986
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>296 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PBCWDF Proceedings of the British Crop Protection Conference - Weeds. (British Crop Protection Council, 2A Kidderminster Rd., Croydon, CRO 2UE, UK) 1976- Volume(issue)/page/year: -,939,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 39(235),30,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
458 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PBCWDF Proceedings of the British Crop Protection Conference - Weeds. (British Crop Protection Council, 2A Kidderminster Rd., Croydon, CRO 2UE, UK) 1976- Volume(issue)/page/year: -,939,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PBCWDF Proceedings of the British Crop Protection Conference - Weeds. (British Crop Protection Council, 2A Kidderminster Rd., Croydon, CRO 2UE, UK) 1976- Volume(issue)/page/year: -,939,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A791,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 39(235),30,1985

Safety Information

[ Hazard Statements ]:
H412

[ Precautionary Statements ]:
P273

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves

[ Risk Phrases ]:
R52/53

[ Safety Phrases ]:
S61

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
AF2500000

[ HS Code ]:
2942000000

Customs

[ HS Code ]: 2942000000

Articles

Method development for determination of fluroxypyr in water.

J. Environ. Sci. Health B 38(4) , 429-40, (2003)

Improved methods for extraction and clean up of fluroxypyr residue in water have been established. Two methods of fluroxypyr extraction were used, namely, Direct Measurement of fluroxypyr and Concentr...

Determination of starane (fluroxypyr) herbicide using flow injection spectrophotometry.

Anal. Sci. 22(1) , 145-6, (2006)

The starane herbicide was spectrophotometrically determined by the diazotization method in a flow injection assembly. Since starane is a substituted pyridyl compound the NH2 group at the p-position wa...

A pathway-specific microarray analysis highlights the complex and co-ordinated transcriptional networks of the developing grain of field-grown barley.

J. Exp. Bot. 60 , 153-67, (2009)

The aim of the study was to describe the molecular and biochemical interactions associated with amino acid biosynthesis and storage protein accumulation in the developing grains of field-grown barley....


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