1-Pyrenedodecanoic acid

Names

[ Name ]:
1-Pyrenedodecanoic acid

[Synonym ]:
MFCD00080927
pyrenedodecanoic acid
Pyrene-1-dodecanoic acid
1-pyrenedoecanoic acid
1-Pyrenedodecanoic acid
12-Pdda

Biological Activity

[Description]:

12-(1-Pyrenyl)dodecanoic acid is a fluorescence probe[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Grieser F, et al. Pressure-area isotherms and fluorescence behaviour of 12-(1-pyrenyl) dodecanoic acid at the air-aqueous solution interface[J]. Chemical physics letters, 1987, 141(1-2): 108-114.

Chemical & Physical Properties

[ Density]:
1.129 g/cm3

[ Boiling Point ]:
594.5ºC at 760 mmHg

[ Molecular Formula ]:
C₂₈H₃₂O₂

[ Molecular Weight ]:
400.55200

[ Flash Point ]:
490.7ºC

[ Exact Mass ]:
400.24000

[ PSA ]:
37.30000

[ LogP ]:
8.11210

[ Index of Refraction ]:
1.653

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Pyrene butanol--an efficient, selective and non-metabolized photosensitizing agent for human myeloid leukemia cells.

Leuk. Res. 16(5) , 453-62, (1992)

Methods for ex vivo purging of neoplastic cells from harvested marrow are being developed to increase the efficacy of autologous transplantation. One approach is selective photosensitization, using se...

Evidence that photodynamic stress kills Zellweger fibroblasts by a nonapoptotic mechanism.

Biochim. Biophys. Acta 1402(1) , 61-9, (1998)

Zellweger fibroblasts, which are devoid of peroxisomes and fail to synthesize plasmalogens, are very sensitive to the killing effect triggered by UV-activated 12-(1-pyrene) dodecanoic acid (P12). Alth...

Analysis of cellular heterogeneity in the response of human leukemic cells to photosensitization induced by pyrene-containing fatty acid.

Leuk. Res. 13(12) , 1099-104, (1989)

Incubation of cells with 12-(1-pyrene) dodecanoic acid (P12) followed by irradiation with ultraviolet light at 366 nm (UVA) resulted in cytotoxicity. We compared the photosensitivity to UVA irradiatio...