Aflatoxin M2

Names

[ Name ]:
Aflatoxin M2

[Synonym ]:
4-Hydroxyaflatoxin B2
Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione,2,3,6a,8,9,9a-hexahydro-9a-hydroxy-4-methoxy
Aflatoxin M(2)
2,3,6a,8,9,9a-hexahydro-9a-hydroxy-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione

Biological Activity

[Description]:

Aflatoxin M2 is a major metabolite of Aflatoxin B1. Aflatoxin M2 is a mycotoxin produced by the fungi Aspergillus flavus and Aspergillus parasiticus. The level of toxicity associated with Aflatoxin is Aflatoxin B1>Aflatoxin M1>Aflatoxin G1>Aflatoxin B2>Aflatoxin M2>Aflatoxin G2[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Kumar P, et al. Aflatoxins: A Global Concern for Food Safety, Human Health and Their Management. Front Microbiol. 2017 Jan 17;7:2170.

Chemical & Physical Properties

[ Density]:
1.62g/cm3

[ Boiling Point ]:
635.6ºC at 760 mmHg

[ Melting Point ]:
181-184ºC

[ Molecular Formula ]:
C₁₇H₁₄O₇

[ Molecular Weight ]:
330.28900

[ Flash Point ]:
6ºC

[ Exact Mass ]:
330.07400

[ PSA ]:
95.20000

[ LogP ]:
1.25690

[ Index of Refraction ]:
1.689

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GY1720000

CAS REGISTRY NUMBER :: 6885-57-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C17-H14-O7

MOLECULAR WEIGHT :: 330.31

WISWESSER LINE NOTATION :: T F5 C6 B665 DOV GV OO QOT&&TTJ AQ LO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: 281 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TELEAY Tetrahedron Letters. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) 1959- Volume(issue)/page/year: -(25),2799,1966 *** REVIEWS *** TOXICOLOGY REVIEW PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 10,85,1974

Safety Information

[ Hazard Codes ]:
T,T+,Xn,F

[ Risk Phrases ]:
45-46-26/27/28-36-20/21/22-11

[ Safety Phrases ]:
53-22-36/37/39-45-36-26-16

[ RIDADR ]:
UN 3172

[ Hazard Class ]:
6.1(a)