Aflatoxin G1-13C17

Names

[ CAS No. ]:
1217444-07-9

[ Name ]:
Aflatoxin G1-13C17

[Synonym ]:
Fully13C-labelled Aflatoxin G1

Biological Activity

[Description]:

Aflatoxin G1-13C17 is the 13C labeled Aflatoxin G1 (HY-N6697)[1]. Aflatoxin G1 is one type of aflatoxins occuring in nature. It is produced by molds, such as Aspergillus flavus and Aspergillus parasiticus. Aflatoxins are hepatogenic, teratogenic, imunosuppressive, and carcinogenic fungal metabolites found in feeds, nuts, wine-grapes, spices, and other grain crops[2][3].

[Related Catalog]:

Research Areas >> Cancer

[In Vitro]

氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220.  

[2]. Sarma UP, et al. Aflatoxins: Implications on Health. Indian J Clin Biochem. 2017 Jun;32(2):124-133.  

[3]. Karaaslan M, et al. Aflatoxins B1, B2, G1, and G2 contamination in ground red peppers commercialized in Sanliurfa, Turkey. Environ Monit Assess. 2015 Apr;187(4):184.  

Chemical & Physical Properties

[ Molecular Formula ]:
13C17H12O7

[ Molecular Weight ]:
345.15

[ Flash Point ]:
2℃

[ Exact Mass ]:
345.11500

[ PSA ]:
84.20000

[ LogP ]:
1.86050

[ Storage condition ]:
?20°C

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302 + H312 + H332-H319

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F,Xn

[ Risk Phrases ]:
11-20/21/22-36

[ Safety Phrases ]:
16-36/37

[ RIDADR ]:
UN 1648 3 / PGII


Related Compounds