NB 001

Names

[ Name ]:
NB 001

[Synonym ]:
nb001
unii-j89qt81nbq
5-{[2-(6-amino-9h-purin-9-yl)ethyl]amino}-1-pentanol
NB 001

Biological Activity

[Description]:

NB001 (HTS 09836) is an adenylcyclase 1 (AC1) inhibitor which has effect on neural and non-neural pain by modulating AC1 activity[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adenylate Cyclase

Research Areas >> Neurological Disease

[Target]

AC1[1]

[References]

[1]. Min Zhuo. Method for treating neuronal and non-neuronal pain. US8124599B2.

Chemical & Physical Properties

[ Density]:
1.37 g/cm3

[ Boiling Point ]:
521.3ºC at 760 mmHg

[ Melting Point ]:
146-148ºC

[ Molecular Formula ]:
C₁₂H₂₀N₆O

[ Molecular Weight ]:
264.32700

[ Flash Point ]:
269.1ºC

[ Exact Mass ]:
264.17000

[ PSA ]:
101.88000

[ LogP ]:
1.13280

[ Storage condition ]:
-20 °C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ RIDADR ]:
UN 2811 6.1 / PGIII

Articles

Estradiol modulates translocator protein (TSPO) and steroid acute regulatory protein (StAR) via protein kinase A (PKA) signaling in hypothalamic astrocytes.

Endocrinology 155(8) , 2976-85, (2014)

The ability of the central nervous system to synthesize steroid hormones has wide-ranging implications for physiology and pathology. Among the proposed roles of neurosteroids is the regulation of the ...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.