4',5,7-Trihydroxy-6-prenylflavone

Names

[ Name ]:
4',5,7-Trihydroxy-6-prenylflavone

[Synonym ]:
4',5,7-trihydroxy-6-prenylflavone
4',5,7-trihydroxy-6-methylflavone
5,7-Dihydroxy-2-(4-hydroxy-phenyl)-6-(3-methyl-but-2-enyl)-1-benzopyran-4-one
5,7,4'-Trihydroxy-6-methyl-flavon
6-prenylapigenin
5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-chromen-4-one
5,7,4'-Trihydroxy-6-methylflavone
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-
6-Methylapigenin
4',5,7-trihydroxy-6-C-prenylflavone

Biological Activity

[Description]:

6-Prenylapigenin is a biologically active flavonoid with anti-tumor activity and antiangiogenic properties. 6-Prenylapigenin exerts cytotoxicity against cancer cells, such as leukemia and solid cancer cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Kuete V, et al. Cytotoxicity and mode of action of four naturally occuring flavonoids from the genus Dorstenia: gancaonin Q, 4-hydroxylonchocarpin, 6-prenylapigenin, and 6,8-diprenyleriodictyol. Planta Med. 2011 Dec;77(18):1984-9.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
586.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₁₈O₅

[ Molecular Weight ]:
338.35

[ Flash Point ]:
212.8±23.6 °C

[ Exact Mass ]:
338.115417

[ PSA ]:
90.90000

[ LogP ]:
4.20

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.667

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%