SGA360

Names

[ Name ]:
SGA360

[Synonym ]:
SGA360

Biological Activity

[Description]:

SGA360 suppress inflammatory SAA1 signaling in an AHR-dependent manner through a mechanism that does not require AHR binding to its cognate response element (partial antagonist)[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[In Vivo]

SGA360 exhibits anti-inflammatory activity in vivo.

[References]

[1]. Iain A Murray, et al. Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties. Chem Res Toxicol. 2010 May 17;23(5):955-66.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₇F₃N₂O₂

[ Molecular Weight ]:
362.34600

[ Exact Mass ]:
362.12400

[ PSA ]:
36.28000

[ LogP ]:
4.92530

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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