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Metazachlor

Names

[ CAS No. ]:
67129-08-2

[ Name ]:
Metazachlor

[Synonym ]:
bas479h
Metazachlor
Pree
MFCD00055509
EINECS 266-583-0
2-chloro-N-(pyrazol-1-ylmethyl)acet-2’,6’-xylidide
2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide
BUTISAN S
Butisan
Track

Biological Activity

[Description]:

Metazachlor is a herbicide of the chloroacetamide class. Metazachlor is an inhibitor of the synthesis of long chain fatty acids and has an effect on cell division or tissue differentiation in the germinating and emerging weed target species[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[Target]

IC50: synthesis of long chain fatty acids[1]


[References]

[1]. Christiane Wiemann, et al. Metazachlor: Mode of action analysis for rat liver tumour formation and human relevance. Toxicology. 2019 Oct 1;426:152282.

Chemical & Physical Properties

[ Density]:
1.19 g/cm3

[ Boiling Point ]:
439.2ºC at 760 mmHg

[ Melting Point ]:
74-78°C

[ Molecular Formula ]:
C14H16ClN3O

[ Molecular Weight ]:
277.74900

[ Flash Point ]:
2 °C

[ Exact Mass ]:
277.09800

[ PSA ]:
38.13000

[ LogP ]:
2.72940

[ Index of Refraction ]:
1.586

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB5442000
CHEMICAL NAME :
Acetamide, 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmet hyl)-
CAS REGISTRY NUMBER :
67129-08-2
BEILSTEIN REFERENCE NO. :
0621550
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C14-H16-Cl-N3-O
MOLECULAR WEIGHT :
277.78
WISWESSER LINE NOTATION :
T5NNJ A1NV1GR B1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C54,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>6810 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,560,1991

Safety Information

[ Symbol ]:

GHS07, GHS08, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H351-H410

[ Precautionary Statements ]:
P273-P301 + P312 + P330-P391-P501

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S36-S26-S16

[ RIDADR ]:
UN 1648 3/PG 2

[ RTECS ]:
AB5442000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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