Triamcinolone diacetate
Names
[ CAS No. ]:
67-78-7
[ Name ]:
Triamcinolone diacetate
[Synonym ]:
Kenacourt
CINO-40
Triamolone 40
Pregna-1,4-diene-3,20-dione, 16,21-bis(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11β,16α)-
(11β,16α)-9-Fluoro-11,17-dihydroxy-3,20-dioxopregna-1,4-diene-16,21-diyl diacetate
21-diacetate
16a,21-Diacetoxy-9a-fluoro-11b,17a-dihydroxy-1,4-pregnadiene-3,20-dione
aristocortsyrup
8357RP
Tracilon
Tedarol
TAC-D
triamcinolone 16,21-diacetate
MFCD00056462
EINECS 200-669-0
(11b,16a)-16,21-Bis(acetyloxy)-9-fluoro-11,17-dihydroxypregna-1,4-diene-3,20-dione
Cenacort
Triamsinolone
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
608.5±55.0 °C at 760 mmHg
[ Melting Point ]:
19-21°C
[ Molecular Formula ]:
C25H31FO8
[ Molecular Weight ]:
478.507
[ Flash Point ]:
321.8±31.5 °C
[ Exact Mass ]:
478.200287
[ PSA ]:
127.20000
[ LogP ]:
2.16
[ Vapour Pressure ]:
0.0±4.0 mmHg at 25°C
[ Index of Refraction ]:
1.573
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU3950000
- CHEMICAL NAME :
- Pregna-1,4-diene-2,20-dione, 9-fluoro-11-beta,16-alpha,17,21-tetrahydroxy-, 16,21-diacetate
- CAS REGISTRY NUMBER :
- 67-78-7
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C25-H31-F-O8
- MOLECULAR WEIGHT :
- 478.56
- WISWESSER LINE NOTATION :
- T F5 E5 B666 GO IO RV AHTTTT&J A1 BF COV1 E1 FV1OV1 H1 H1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 87500 ug/kg
- SEX/DURATION :
- female 15-17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord)
- REFERENCE :
- BBACAQ Biochimica et Biophysica Acta. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1947- Volume(issue)/page/year: 385,257,1975
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 3200 ug/kg
- SEX/DURATION :
- female 11-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
- REFERENCE :
- SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 149,862,1965 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81555 No. of Facilities: 44 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 1469 (estimated) No. of Female Employees: 1098 (estimated)
Safety Information
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R10:Flammable.
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 3272 3/PG 3
[ WGK Germany ]:
3
[ Packaging Group ]:
III
[ Hazard Class ]:
3
[ HS Code ]:
29349990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 29349990