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5-O-Benzoyl-1,2-O-(1-methylethylidene)pentofuranos-3-ulose

Names

[ CAS No. ]:
6698-46-0

[ Name ]:
5-O-Benzoyl-1,2-O-(1-methylethylidene)pentofuranos-3-ulose

[Synonym ]:
Pentofuranos-3-ulose, 1,2-O-(1-methylethylidene)-, 5-benzoate
(2,2-dimethyl-6-oxo-3a,6a-dihydrofuro[2,3-d][1,3]dioxol-5-yl)methylbenzoate
5-O-Benzoyl-1,2-O-(1-methylethylidene)pentofuranos-3-ulose
5-O-Benzoyl-1,2-O-isopropylidenepentofuranos-3-ulose

Biological Activity

[Description]:

5-O-Benzoyl-1,2-di-O-isopropylidene-3-keto-alpha-D-xylofuranoside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
411.0±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C15H16O6

[ Molecular Weight ]:
292.28

[ Flash Point ]:
182.4±28.8 °C

[ Exact Mass ]:
292.094696

[ PSA ]:
71.06000

[ LogP ]:
3.29

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.522

Precursor & DownStream

Precursor

DownStream