NCGC00379308

Names

[ Name ]:
NCGC00379308

Biological Activity

[Description]:

D3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 by direct TSHR activation and potentiates TSH-mediated preosteoblast differentiation in vitro[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> TSH Receptor

Research Areas >> Others

[Target]

Thyrotropin receptor (TSHR)[1]

[References]

[1]. Neumann S, et al. Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro. J Pharmacol Exp Ther. 2018 Jan;364(1):38-45.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₃N₅

[ Molecular Weight ]:
333.43

Related Compounds

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