temocillin

Names

[ Name ]:
temocillin

[Synonym ]:
Temocilline [INN-French]
Temocillinum
Temocilline
Temocillina [INN-Spanish]
Temocillina
Temocillin
EINECS 266-184-1
Temocillinum [INN-Latin]
(2S,5R,6S)-6-[(2-carboxy-2-thiophen-3-ylacetyl)amino]-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Biological Activity

[Description]:

Temocillin, a 6-alpha-methoxy penicillin derivative, is a semisynthetic beta-lactam antibiotic with a spectrum of activity against most aerobic Gram-negative bacteria[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Alexandre K, et al. Pharmacokinetics and Pharmacodynamics of Temocillin. Clin Pharmacokinet. 2018 Mar;57(3):287-296.

Chemical & Physical Properties

[ Density]:
1.6 g/cm3

[ Boiling Point ]:
761.9ºC at 760 mmHg

[ Molecular Formula ]:
C₁₆H₁₈N₂O₇S₂

[ Molecular Weight ]:
414.45300

[ Exact Mass ]:
414.05600

[ PSA ]:
186.78000

[ LogP ]:
0.85090

[ Index of Refraction ]:
1.675

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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