Z-Gln-Gly-OH

Names

[ Name ]:
Z-Gln-Gly-OH

[Synonym ]:
Z-Gln-Gly
N-carbobenzyloxy glutaminyl glycine
benzyloxycarbonyl-Gln-Gly
MFCD00055926
Cbz-L-Gln-Gly
Z-Gln-Gly-OH

Biological Activity

[Description]:

(S)-2-(5-Amino-2-(((benzyloxy)carbonyl)amino)-5-oxopentanamido)acetic acid is a Glycine (HY-Y0966) derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.339g/cm3

[ Boiling Point ]:
748ºC at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₉N₃O₆

[ Molecular Weight ]:
337.32800

[ Flash Point ]:
406.2ºC

[ Exact Mass ]:
337.12700

[ PSA ]:
147.82000

[ LogP ]:
1.22980

[ Appearance of Characters ]:
Solid

[ Index of Refraction ]:
1.567

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

A direct continuous spectrophotometric assay for transglutaminase activity.

Anal. Biochem. 285 , 16-20, (2000)

Herein we report the development of a direct and continuous spectrophotometric method for determining transglutaminase (TGase) activity by using N,N-dimethyl-1,4-phenylenediamine (DMPDA) as a gamma-gl...

Chemoenzymatic synthesis of neoglycopeptides: application to an alpha-Gal-terminated neoglycopeptide.

J. Org. Chem. 66 , 2948-56, (2001)

A novel methodology for the enzymatic preparation from suitably derivatized oligosaccharides of N-linked neoglycopeptides using the microbial glutaminyl-peptide gamma-glutamyl transferase, transglutam...

Kinetic analysis of the action of tissue transglutaminase on peptide and protein substrates.

Biochemistry 42 , 9466-9481, (2003)

Tissue transglutaminase (TGase) catalyzes transfer of gamma-acyl moieties of Gln residues in peptides or protein substrates to either water or amine nucleophiles through an acyl-enzyme intermediate fo...