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Angeloylgomisin H

Names

[ CAS No. ]:
66056-22-2

[ Name ]:
Angeloylgomisin H

[Synonym ]:
UNII:Y16R9MI4T6
Angeloylgomisin H
(6S,7S)-7-Hydroxy-2,3,10,11,12-pentamethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c][8]annulen-1-yl (2Z)-2-methyl-2-butenoate
2-Butenoic acid, 2-methyl-, (6S,7S)-5,6,7,8-tetrahydro-7-hydroxy-2,3,10,11,12-pentamethoxy-6,7-dimethyldibenzo[a,c]cycloocten-1-yl ester, (2Z)-

Biological Activity

[Description]:

Angeloylgomisin H, as a major lignin extract of Schisandra rubriflora, has the potential to improve insulin-stimulated glucose uptake by activating PPAR-γ[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR
Research Areas >> Metabolic Disease

[Target]

PPAR-γ


[References]

[1]. Chen S, et al. Pharmacokinetic and bioavailability study of angeloylgomisin H in rat plasma by UPLC-MS/MS. Int J Clin Exp Med. 2015 Oct 15;8(10):17968-76.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
656.3±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C28H36O8

[ Molecular Weight ]:
500.581

[ Flash Point ]:
212.3±25.0 °C

[ Exact Mass ]:
500.241028

[ PSA ]:
92.68000

[ LogP ]:
4.92

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.539

[ Storage condition ]:
2-8℃

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds