4H-Pyrrolo[3,2-d]pyrimidin-4-one,2-amino-3,5-dihydro-

Names

[ CAS No. ]:
65996-58-9

[ Name ]:
4H-Pyrrolo[3,2-d]pyrimidin-4-one,2-amino-3,5-dihydro-

[Synonym ]:
9-Deazaguanidine
9-Deazaguanine
9-carbaguanine
9DG

Biological Activity

[Description]:

9-Deazaguanine is a nucleoside analog with potent inhibitory activity against purine nucleoside phosphorylase (PNP)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Beata Wielgus-Kutrowska, et al. Trimeric purine nucleoside phosphorylase: exploring postulated one-third-of-the-sites binding in the transition state. Bioorg Med Chem. 2012 Nov 15;20(22):6758-69.

Chemical & Physical Properties

[ Density]:
1.87g/cm3

[ Boiling Point ]:
452.7ºC at 760mmHg

[ Molecular Formula ]:
C₆H₆N₄O

[ Molecular Weight ]:
150.14

[ Flash Point ]:
227.6ºC

[ Exact Mass ]:
150.05400

[ PSA ]:
87.56000

[ LogP ]:
0.41460

[ Index of Refraction ]:
1.89

[ Storage condition ]:
Refrigerator

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%