Lactupicrin

Names

[ Name ]:
Lactupicrin

[Synonym ]:
Lactupicrin
Benzeneacetic acid,4-hydroxy-,2,3,3a,4,5,7,9a,9b-octahydro-9-(hydroxymethyl)-6-methyl-3-methylene-2,7-dioxoazuleno(4,5-b)furan-4-yl ester,(3aR-(3aalpha,4alpha,9aalpha,9bbeta))

Biological Activity

[Description]:

Lactupicrin (Lactucopicrin) is a characteristic bitter sesquiterpene lactone that can relieve pain. Lactupicrin exhibits atheroprotective effect[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

Research Areas >> Neurological Disease

[References]

[1]. Wesołowska A, et, al. Analgesic and sedative activities of lactucin and some lactucin-like guaianolides in mice. J Ethnopharmacol. 2006 Sep 19;107(2):254-8.

[2]. Li Q, et, al. Terpene Lactucopicrin Limits Macrophage Foam Cell Formation by a Reduction of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Lipid Rafts. Mol Nutr Food Res. 2022 Feb;66(4):e2100905.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₂O₇

[ Molecular Weight ]:
410.41700

[ Exact Mass ]:
410.13700

[ PSA ]:
110.13000

[ LogP ]:
1.78210

Related Compounds

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