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3-Campholenyl-2-butanol

Names

[ CAS No. ]:
65113-99-7

[ Name ]:
3-Campholenyl-2-butanol

[Synonym ]:
EINECS 265-453-0
sandal pentanol
Sandalore

Biological Activity

[Description]:

3-Campholenyl-2-butanol, a synthetic sandalwood odorant, is a selective olfactory receptor OR2AT4 agonist. 3-Campholenyl-2-butanol prolongs human hair growth ex vivo by decreasing apoptosis and increasing production of the anagen-prolonging growth factor IGF-1 in the outer root sheath (ORS)[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Others

[In Vitro]

3-Campholenyl-2-butanol (500 μM; 6 days) retards spontaneous hair follicle (HF) regression (catagen development) ex vivo and significantly reduces hair matrix keratinocyte apoptosis[1].

[References]

[1]. Chiamulera C, et al. Effect of NMDA- and strychnine-insensitive glycine site antagonists on NMDA-mediated convulsions and learning. Psychopharmacology (Berl). 1990;102(4):551-552.

Chemical & Physical Properties

[ Density]:
0.895-0.904

[ Boiling Point ]:
275.8ºC at 760 mmHg

[ Melting Point ]:
>100ºC

[ Molecular Formula ]:
C14H26O

[ Molecular Weight ]:
210.35600

[ Flash Point ]:
>100ºC

[ Exact Mass ]:
210.19800

[ PSA ]:
20.23000

[ LogP ]:
3.77590

[ Index of Refraction ]:
1.4700-1.4760

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
N

Related Compounds