N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
Names
[ CAS No. ]:
64987-85-5
[ Name ]:
N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
[Synonym ]:
MFCD00009634
1-[(4-{[(2,5-Dioxopyrrolidin-1-yl)oxy]carbonyl}cyclohexyl)methyl]-1H-pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 1-((4-(((2,5-dioxo-1-pyrrolidinyl)oxy)carbonyl)cyclohexyl)methyl)-
N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
1-[(4-{[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl}cyclohexyl)methyl]-1H-pyrrole-2,5-dione
1H-pyrrole-2,5-dione, 1-[[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-
N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
501.7±42.0 °C at 760 mmHg
[ Melting Point ]:
180-182 °C(lit.)
[ Molecular Formula ]:
C16H18N2O6
[ Molecular Weight ]:
334.324
[ Flash Point ]:
257.2±27.9 °C
[ Exact Mass ]:
334.116486
[ PSA ]:
101.06000
[ LogP ]:
-0.39
[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C
[ Index of Refraction ]:
1.598
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
chloroform: 50 mg/mL
MSDS
Safety Information
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2925190090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2925190090
[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
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Antibody-drug conjugates (ADCs) have evolved as a new class of potent cancer therapeutics. We here report on the development of ADCs with specificity for the B-cell lineage specific (surface) antigen ...
Solid formulations by a nanocrystal approach: critical process parameters regarding scale-ability of nanocrystals for tableting applications.Int. J. Pharm. 485 , 77-86, (2015)
Nanocrystallization is among the foremost drug delivery platform approaches for the commercial development of poorly soluble drugs. There exists an urge to enable a universal shift of the production o...
An NIR-triggered and thermally responsive drug delivery platform through DNA/copper sulfide gates.Nanoscale 7 , 12614-24, (2015)
Nanomaterials for effective drug delivery require zero pre-release and on-demand release of therapeutic drugs. In this work we demonstrate a novel drug delivery system composed of a mesoporous silica ...