Ethyl 2-oxo-4-phenylbutanoate
Names
[ CAS No. ]:
64920-29-2
[ Name ]:
Ethyl 2-oxo-4-phenylbutanoate
[Synonym ]:
Ethyl 2-oxo-4-phenylbutanoate
2-oxo-4-phenyl-butyric acid ethyl ester
BENZYLPYRUVIC ACID ETHYL ESTER
EINECS 265-276-9
2-oxo-4-phenylhexanoate
MFCD00037533
Ethy 2-oxo-4-phenylbutyrate
Ethyl-2-oxo-4-phenylbutanoat
ethyl 2-keto-4-phenylbutyrate
4-phenyl-2-oxobutyric acid ethyl ester
Benzenebutanoic acid, α-oxo-, ethyl ester
Ethyl 4-phenyl-2-oxobutanoate
ethyl 2-oxo-4-phenyl-butyrate
KETO ESTER
ETHYL-2 OXO-4 PHENYL BUTANOATE
ETHYL BENZYLPYRUVATE
ETHYL-2-OXO-4-PHENYLBUTRATE
2-oxo-4-phenylbutanoic acid ethyl ester
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
309.0±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C12H14O3
[ Molecular Weight ]:
206.238
[ Flash Point ]:
140.0±19.2 °C
[ Exact Mass ]:
206.094299
[ PSA ]:
43.37000
[ LogP ]:
2.24
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.506
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S23-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2918300090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2918300090
[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
Org. Lett. 14(8) , 1982-5, (2012)
A new reductase, CgKR2, with the ability to reduce ethyl 2-oxo-4-phenylbutyrate (OPBE) to ethyl (R)-2-hydroxy-4-phenylbutyrate ((R)-HPBE), an important chiral precursor for angiotensin-converting enzy...
Scalable biocatalytic synthesis of optically pure ethyl (R)-2-hydroxy-4-phenylbutyrate using a recombinant E. coli with high catalyst yield.J. Biotechnol. 168(4) , 493-8, (2013)
Ethyl (R)-2-hydroxy-4-phenylbutanoate [(R)-HPBE] is a versatile and important chiral intermediate for the synthesis of angiotensin-converting enzyme (ACE) inhibitors. Recombinant E. coli strain coexpr...
Effect of ionic liquid [BMIM][PF6] on asymmetric reduction of ethyl 2-oxo-4-phenylbutyrate by Saccharomyces cerevisiae.J. Ind. Microbiol. Biotechnol. 35(11) , 1419-24, (2008)
The effect of ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF6]) on the asymmetric reduction of ethyl 2-oxo-4-phenylbutyrate (EOPB) to synthesize optical active ethyl 2-hydroxy...