Decan-1,10-diamin
Names
[ CAS No. ]:
646-25-3
[ Name ]:
Decan-1,10-diamin
[Synonym ]:
1,10-Decanediamine
Decan-1,10-diamin
1,10-DIAMINODECANE
Decamethylenediamine
Decane-1,10-diamine
MFCD00008151
Z10Z
EINECS 211-471-9
1,10-Decamethylenediamine
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
271.1±0.0 °C at 760 mmHg
[ Melting Point ]:
62 °C
[ Molecular Formula ]:
C10H24N2
[ Molecular Weight ]:
172.311
[ Flash Point ]:
127.1±24.8 °C
[ Exact Mass ]:
172.193954
[ PSA ]:
52.04000
[ LogP ]:
2.17
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.464
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HD7175000
- CHEMICAL NAME :
- 1,10-Decanediamine
- CAS REGISTRY NUMBER :
- 646-25-3
- BEILSTEIN REFERENCE NO. :
- 1738591
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C10-H24-N2
- MOLECULAR WEIGHT :
- 172.36
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 4,377,1952
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 3259 8/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
HD7175000
[ Hazard Class ]:
8.0
[ HS Code ]:
2921290000
Synthetic Route
Customs
[ HS Code ]: 2921290000
[ Summary ]:
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
Nat. Chem. Biol. 3(5) , 268-273, (2007)
The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.Nat. Chem. Biol. 5 , 765-71, (2009)
Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened...
Antitubercular activity of alpha,omega-diaminoalkanes, H2N(CH2)nNH2.Bioorg. Med. Chem. Lett. 19 , 4937-8, (2009)
A series of 11 alpha,omega-diaminoalkanes, (H(2)N(CH(2))(n)NH(2), n=2-12) have been evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis H37Rv. Compounds, (H(2)N(CH(2...