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o-Tolylacetic acid

Names

[ CAS No. ]:
644-36-0

[ Name ]:
o-Tolylacetic acid

[Synonym ]:
(2-Methylphenyl)acetic acid
2-(2-methylphenyl)acetic acid
MFCD00004328
O-Tolylacetic acid
EINECS 211-416-9
Benzeneacetic acid, 2-methyl-

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
279.3±9.0 °C at 760 mmHg

[ Melting Point ]:
88-90 °C(lit.)

[ Molecular Formula ]:
C9H10O2

[ Molecular Weight ]:
150.174

[ Flash Point ]:
176.5±13.9 °C

[ Exact Mass ]:
150.068085

[ PSA ]:
37.30000

[ LogP ]:
1.97

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.546

[ Water Solubility ]:
insoluble

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ HS Code ]:
2942000000

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse.

J. Neurosci. 35(14) , 5664-79, (2015)

The Ca(2+) channelopathies caused by mutations of the CACNA1A gene that encodes the pore-forming subunit of the human Cav2.1 (P/Q-type) voltage-gated Ca(2+) channel include episodic ataxia type 2 (EA2...

Homer protein-metabotropic glutamate receptor binding regulates endocannabinoid signaling and affects hyperexcitability in a mouse model of fragile X syndrome.

J. Neurosci. 35(9) , 3938-45, (2015)

The Fmr1 knock-out mouse model of fragile X syndrome (Fmr1(-/y)) has an epileptogenic phenotype that is triggered by group I metabotropic glutamate receptor (mGluR) activation. We found that a membran...

Visualization of Ca2+ Filling Mechanisms upon Synaptic Inputs in the Endoplasmic Reticulum of Cerebellar Purkinje Cells.

J. Neurosci. 35 , 15837-46, (2015)

The endoplasmic reticulum (ER) plays crucial roles in intracellular Ca(2+) signaling, serving as both a source and sink of Ca(2+), and regulating a variety of physiological and pathophysiological even...


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Related Compounds