Methyl 2,3,5-tri-O-benzyl-D-ribofuranoside

Names

[ Name ]:
Methyl 2,3,5-tri-O-benzyl-D-ribofuranoside

[Synonym ]:
2,3,5-tri-O-benzyl-1-O-methyl-D-ribose
Methyl 2,3,5-tri-O-benzyl-D-ribofuranoside
methyl 2,3,4-tri-O-benzylribofuranoside
methyl-2,3,5-tri-O-benzyl-D-riboside
D-Ribofuranoside, methyl 2,3,5-tris-O-(phenylmethyl)-
methyl tri-O-benzyl-D-ribofuranoside

Biological Activity

[Description]:

Methyl 2,3,5-tri-O-benzyl-D-ribofuranoside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
552.6±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₇H₃₀O₅

[ Molecular Weight ]:
434.52

[ Flash Point ]:
217.4±30.0 °C

[ Exact Mass ]:
434.209320

[ PSA ]:
46.15000

[ LogP ]:
6.48

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.587

Precursor & DownStream

Precursor

DownStream

Related Compounds

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