Tridecanoic acid-d2

Names

[ CAS No. ]:
64118-44-1

[ Name ]:
Tridecanoic acid-d2

Biological Activity

[Description]:

Tridecanoic acid-d2 is the deuterium labeled Tridecanoic acid. Tridecanoic acid (N-Tridecanoic acid), a 13-carbon medium-chain saturated fatty acid, can serve as an antipersister and antibiofilm agent that may be applied to research bacterial infections. Tridecanoic acid inhibits Escherichia coli persistence and biofilm formation[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Jin X, et, al. Undecanoic acid, lauric acid, and N-tridecanoic acid inhibit Escherichia coli persistence and biofilm formation. J Microbiol Biotechnol. 2020 Oct 13.

Chemical & Physical Properties

[ Boiling Point ]:
236ºC/100 mmHg

[ Melting Point ]:
41-42ºC(lit.)

[ Molecular Formula ]:
C13H24D2O2

[ Molecular Weight ]:
216.36

[ Flash Point ]:
113ºC

[ Exact Mass ]:
216.20600

[ PSA ]:
37.30000

[ LogP ]:
4.38200

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds