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Chartreusin

Names

[ CAS No. ]:
6377-18-0

[ Name ]:
Chartreusin

[Synonym ]:
CHARTREUSIN
antibioticx-465a
u-7257
chartreusin from streptomyces*chartreusis

Biological Activity

[Description]:

Chartreusin is an antibiotic that is active against certain Gram-positive organisms and mycobacteria. Chartreusin is also active against the Micrococcus fiyogenes v. aureus phage[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Leach B E, et al. Chartreusin, a new antibiotic produced by Streptomyces chartreusis, a new species. Journal of the American Chemical Society, 1953, 75(16): 4011-4012.

Chemical & Physical Properties

[ Density]:
1.63g/cm3

[ Boiling Point ]:
945.5ºC at 760 mmHg

[ Molecular Formula ]:
C32H32O14

[ Molecular Weight ]:
640.58800

[ Flash Point ]:
307.8ºC

[ Exact Mass ]:
640.17900

[ PSA ]:
207.72000

[ LogP ]:
1.36980

[ Index of Refraction ]:
1.718

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FL7350000
CHEMICAL NAME :
Chartreusin
CAS REGISTRY NUMBER :
6377-18-0
BEILSTEIN REFERENCE NO. :
0075649
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C32-H32-O14
MOLECULAR WEIGHT :
640.64
WISWESSER LINE NOTATION :
T B66 K666 2AB T HVO SVOJ F1 QQ LO- BT6OTJ DQ EQ F1 CO- BT6OTJ CQ DO1 EQ F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Human Cells - not otherwise specified
DOSE/DURATION :
5 mg/L
REFERENCE :
RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 34,173,1981

Related Compounds

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