Foscarnet sodium
Names
[ CAS No. ]:
63585-09-1
[ Name ]:
Foscarnet sodium
[Synonym ]:
Phosphoranecarboxylic acid, 1,1-dihydroxy-, oxide, sodium salt (1:3)
Trisodium dioxidophosphinecarboxylate oxide
Foscanet sodium
Triapten
Foscarnet sodium
phosphoranecarboxylic acid, dihydroxy-, oxide, trisodium salt
foscarnet sodim
MFCD00013973
trisodium dioxidophosphanecarboxylate oxide
SODIUM FOSCARNET
Phenytion Sodium
Foscavir
trisodium phosphonoformate
FOSCARNET TRISODIUM SALT
phosphonoformate sodium salt
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
[References]
Chemical & Physical Properties
[ Boiling Point ]:
270-272°C
[ Melting Point ]:
62-65 °C(lit.)
[ Molecular Formula ]:
CNa3O5P
[ Molecular Weight ]:
191.951
[ Flash Point ]:
270-272°C
[ Exact Mass ]:
191.917648
[ PSA ]:
113.13000
[ Storage condition ]:
-20℃
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SY8200000
- CHEMICAL NAME :
- Phosphinecarboxylic acid, dihydroxy-, oxide, trisodium salt
- CAS REGISTRY NUMBER :
- 63585-09-1
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C-O5-P.3Na
- MOLECULAR WEIGHT :
- 191.95
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 2400 mg/kg/6D-I
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- REFERENCE :
- LANCAO Lancet. (7 Adam St., London WC2N 6AD, UK) V.1- 1823- Volume(issue)/page/year: 2,216,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 384 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4215113
Safety Information
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ Packaging Group ]:
II
[ HS Code ]:
2942000000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2942000000